All posts by Leo Goldstein

Build Back Better

What does Build Back Better mean? Something should be destroyed to build it back. Where have I heard it? The Communist International, in Russian, second verse:

Весь Мир насилья мы разрушим
До основанья, а затем
Мы наш, мы новый Мир построим;
Кто был ничем, тот станет всем.
We will destroy this whole violent World
To the ground, and then
We will Build Back Better;
Those who were nothing will become everything.

Well, more accurate translation of the third line is We will build our new World, but the meaning is the same. Notice that they need to destroy the whole World, no less.

Merck Ignores Molnupiravir Cytotoxicity

My article Merck Ignores Molnupiravir’s Cytotoxicity is published in Trial Site News behind paywall. This is a free copy Molnupiravir-Cytotoxic-Merck.PDF.

The fraudulent and malicious marketing of Molnupiravir by Merck explains its campaign against Ivermectin. Its anti-Ivermectin statements should be considered part of its Molnupiravir marketing, and Merck should be held accountable. Continue reading Merck Ignores Molnupiravir Cytotoxicity

Is Molnupiravir a Global Catastrophic Threat?

This article was first published by TrialSiteNews behind a paywall.

Merck’s Molnupiravir (also known as EIDD-2801 and MK-4482) is a mutagenic nucleotide analogue [1]. It introduces errors in the SARS-COV-2 RNA at the time of replication after proofreading, and causes lethal mutagenesis [2]. This threatens to accelerate the evolution of the coronavirus.

Any major variant of the coronavirus represents local optimum (in mutations space), maximizing coronavirus’ fitness. One- or two-point mutations cannot accomplish this. A new variant can only rise through the change of the virus-host-conditions systems, or through larger mutations set. Even a moderate increase in the point mutations frequency causes a big increase in the frequency of multi-point mutations and dangerous recombinations. Such events are too rare to be caught in small trials, but inevitable in large populations, and might lead to catastrophic consequences. The authorization and broad use of Molnupiravir is likely to breed very dangerous SARS-COV-2 variants. Continue reading Is Molnupiravir a Global Catastrophic Threat?

Live Unattenuated/Attenuated Virus Vaccines for COVID-19

2021-10-04, preprint, self-published Cochrane-style

Live Unattenuated/Attenuated Virus Vaccines for COVID-19

Leo Goldstein

Introduction

Among the many vaccine technologies attempted for COVID-19 vaccines, the oldest technology – live unattenuated virus (LUV) vaccine – has hardly been mentioned. For the purposes of this article, a LUV vaccine refers to the process of administering a small amount of unattenuated virus in conjunction with the anti-viral against it [1]. Continue reading Live Unattenuated/Attenuated Virus Vaccines for COVID-19

Suppression of the Delta-Specific Vaccine

A Delta-specific version of COVID-19 vaccine has been developed months ago. Those who need a booster shot could have received it now. However, the FDA/CDC/NIH blocked its clinical trials and silenced even a discussion of it.

The current Delta strain (or serotype) of SARS-COV-2, now dominant in the US, is a far cry from the original Wuhan strain. All current vaccines target the original Wuhan strain. Both Moderna and Pfizer vaccines were developed and emergency authorized in 2020. The Delta strain is the result of the coronavirus evolving to evade limited immunity conferred by those vaccines.

The neutralizing effect of the antibodies elicited by the 2020 vaccines is 6-8x lower against the Delta than against the original Wuhan strain 1, 2. The higher replication rates of the Delta strain/serotype decrease vaccine effectiveness even further.

Thus, the original 2020 vaccines were not designed, and are not effective (except for few months as prophylaxis) against the current Delta strain / serotype. All the dangers and harms remain or become worse. Continue reading Suppression of the Delta-Specific Vaccine

Low Risk Natural Immunization against COVID-19

2021-09-21,  preprint, v.2.1, self-published Cochrane-style. Immunization-PVPI-v2.1.pdf 

Low Risk Natural Immunization against COVID-19

Medical Protocol Proposal

Leo Goldstein [1]

This theoretical article, building on the previous Protocol for Self Immunization against COVID-19 (Goldstein, 2021b), proposes cleaning the upper respiratory tract by gargling, mouth rinsing, and nasal irrigation (GMN) with PVP-I or common oral antiseptics as the infection stopping treatment. Such cleaning is intended to stop progression of a COVID-19 infection, after it has reached the minimum level necessary for immunity acquisition, and to constrain it to nasopharynx. GMN is already included in prophylaxis and/or early treatment of COVID-19 (FLCCC, 2021) , (Marik, 2021). The advantage of this proposed protocol is that the infection is interrupted early before symptoms appear. Continue reading Low Risk Natural Immunization against COVID-19

Why was Measles added to the list of quarantinable diseases?

The Demented Puppet has signed a (putative) executive order, adding measles to the list of quarantinable diseases.

The quarantine laws allow all levels of governments to isolate, separate, and restrict movement of sick persons and those who were in their proximity. Except for COVID-19 and pandemic flu, this quarantinable diseases list only included very rare and dangerous infectious diseases such as Cholera, Diphtheria, Infectious Tuberculosis, Plague, Smallpox, Yellow fever, viral hemorrhagic fevers (Ebola and similar), severe acute respiratory syndromes (SARS, MERS). Each disease on the list is either highly lethal or epidemic, and most of them are both. Continue reading Why was Measles added to the list of quarantinable diseases?

FDA Fiction — Fictional Approval of COVID-19 Vaccine

As many have correctly noticed, the FDA has not approved any of the COVID-19 vaccines. All currently used Covid-19 vaccines are still under Emergency Use Authorization (EUA). So, the obvious questions are:

  1. Has the FDA approved the BioNTech COMIRNATY vaccine, as alleged?
  2. Why would the FDA approve a vaccine not supplied to the US, instead of approving the equivalent formulation, manufactured and distributed by Pfizer[1], which has been injected in half of the US population, allegedly with enormous success?
  3. Finally, why has the FDA created an artificial legal distinction[2] between batches of the same product, manufactured at different plants?

The FDA Approval Letter in the question is dated by August 23 and is signed by two directors of CBER offices. One of those directors is Marion Gruber, PhD, who has announced her future resignation, due to the CDC’s attempts to force an approval of a COVID-19 vaccine. Continue reading FDA Fiction — Fictional Approval of COVID-19 Vaccine

Current COVID-19 vaccines are obsolete

All currently circulating strains of SARS-COV-2 (i.e., Delta sub-variants) have spike mutations L452R & T478K, disabling most vaccine induced antibodies. These strains also have aT19R mutation, disrupting epitopes in spike NTD. Many NTD-directed antibodies are known to cause ADE, especially when the epitopes which they target are disrupted.

These L452R/Q & T478K have been mutations of concern for many months. Pfizer & Moderna have had plenty of time to modify their vaccines and/or make a booster with the new spike mRNA. Surprisingly however, the Biden-Harris regime has not demanded any modifications to improve the vaccine to make it effective against the current SARS-COV-2 variants.

All the side effects and other harms remain.

Medical hypothesis about the evolving Delta variant and its early treatment

2021-09-09,  preprint, self-published Cochrane-style. TreatingEvolvingDelta-Zinc.PDF 

Bullet Points
  • The current coronavirus variant has a shorter incubation period and a higher replication rate than previous variants. This necessitates an earlier start of anti-viral treatment despite the efforts of certain forces to hinder access to the necessary medications.
  • The current coronavirus variant is capable of cell-cell fusion. This may decrease the effectiveness of antibodies and some drugs. One way to compensate for this is with higher amounts of zinc and its ionophores, especially hydroxychloroquine.

Continue reading Medical hypothesis about the evolving Delta variant and its early treatment

Delta Subvariants AY.3, AY.4, and A.25 are Dominant. The CDC Lies.

2021-10-17: OBSOLETE, except that the CDC continues to lie. See Delta Growth for updated information.

2021-09-06: updated with the sub-variant AY.25. The situation is changing rapidly. This article is not being updated

The CDC uses W.H.O’s classification of the SARS-COV2 variants. W.H.O has failed to elevate Delta sub-variants into full variants when such a classification is more than warranted. Consequently, what has been called Delta (B.1.617.2) since May 2021 is a mix of many sub-variants with different properties. This confused clinicians and the CDC added to this confusion. Continue reading Delta Subvariants AY.3, AY.4, and A.25 are Dominant. The CDC Lies.

Democrats Sabotage Texas Response to COVID-19

Democrat and Democrat-Socialist politicians control the largest cities and counties in Texas. In the fight against the Wuhan coronavirus, many of these politicians seem to be on the side of the coronavirus. Instead of supporting early treatment to prevent hospitalizations and deaths, they force masking and deceive or even bribe young people into getting the alleged “vaccine”. The “top” three counties leading in COVID-19 deaths, are all Democrat-led. Texas will continue to suffer a disproportionate share of COVID-19 deaths until this sabotage is overcome.

Continue reading Democrats Sabotage Texas Response to COVID-19

Importance of Oral and Nasal Hygiene in COVID-19 Pandemic

We are constantly reminded to wash our hands with soap or alcoholic solutions that kill the coronavirus. But the coronavirus does not live on hands. COVID-19 starts in the upper respiratory tract (URT). The largest load develops in the nasopharynx. From there, it spreads into the lungs through the pharynx mucosal surfaces. Therefore, it stands to reason that we should frequently cleanse the upper respiratory tract: nasal cavity, oral cavity, nasopharynx, and oropharynx. The most promising antiseptic is Povidone-Iodine (PVP-I), because it has been used for this purpose in dentistry and otolaryngology for decades. Continue reading Importance of Oral and Nasal Hygiene in COVID-19 Pandemic

C19 Vaccines are not for Immune Persons. Prophylaxis before C19 Vaccine? Mucosal Immunity?

C19 Vaccines were not formulated for people who have recovered from COVID-19

The clinical trials for the mRNA vaccines excluded participants who were seropositive for COVID-19. Thus, the trials safety and efficacy results are applicable only to individuals seronegative for COVID-19 antibodies. Seropositive persons already have antibodies to COVID-19 and are therefore likely immune.  Thus, they do not need the mRNA vaccine and they are likely to have stronger adverse effects from vaccination.

Based on the CDC’s own data, most people <65 who receive are now being vaccinated already have natural immunity.

Antiviral Prophylaxis with Vaccine?

2021-08-26. Vaccination decreases innate immunity for some time after the each shot. For COVID-19 in adults, this decrease in the innate immunity is likely compensated by the vaccine-elicited adaptive immunity. This compensation might become sufficiently effective as soon as 10 days after the first shot, although some estimates are longer.

COVID-19 vaccination is conducted in areas where the disease is present, and the person might be already infected in time of vaccination, or become infected within those 10 days. Notice that the vaccine elicited immunity is less effective against the Delta variant, and is likely to be even less effective against future variants. Continue reading C19 Vaccines are not for Immune Persons. Prophylaxis before C19 Vaccine? Mucosal Immunity?